The casting is very good good. SNL fans will appreciate seeing Kevin Nealon and Tim Meadows (as the Sheriff). Andy Richter is good as Uncle Nate, and Doris Roberts is funny as 'Nana'. The most entertaining character is Ricky Dillman, who is the boyfriend of Tom's sister Bethany. He is a liar, and is older than he admitted. That fact turns out to be very useful when he is stuck with a dart :)
A very good movie. Lots of action, and very funny.
No content warnings. I took my nephews, ages 9 - 14 to see this, and there was nothing objectionable.